Research Technologist 1
College of Medicine
2d ago


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Pediatric Hematology-Oncology division is seeking a qualified, motivated Research Technician I to join a talented research team focusing on developmental therapeutic studies to identify and validate potential drugs for treatment of hematologic malignancies.

Incumbent will develop and maintain patient derived xenograft models of disease to explore therapeutic interventions. We are looking for someone who is enthusiastic and ambitious to learn.

Applicant needs to be detail oriented and follow SOPs and experimental plans.

Responsibilities :

  • Execution of experiments, data analysis, record keeping, ordering lab supplies, preparing IACUC protocols, etc.
  • Generate Patient Derived Xenografts, bone marrow and spleen cell isolation
  • Maintain laboratory equipment and certifications
  • Maintain inventory of raw materials, buffers, and reagents
  • Handle breeding colony
  • Perform common assay like Western Blot, and proliferation
  • Maintain cell culture
  • Participate in troubleshooting of processes
  • Complete projects by assisting project team; attend and participate in team, department, and all-hands meetings.
  • Qualifications :

  • Bachelor’s Degree (BS) or Masters in related science field required
  • Hands on experience with animal husbandry, breeding, drug administration (IP, IV, SC, IM, IF, oral gavage), necropsy, bleeding, data collection, and interacting with veterinary staff in animal facility
  • Western Blot, ELISA, ICC / IHC, and Flow cytometry transfection
  • Strong knowledge of multicolor flow and data analysis
  • Knowledge of primary cell culture techniques and database, cytotoxicity assay, colony formation assay, drug combination studies and analysis.
  • Must be willing to work occasional weekends, and holidays

    Pursuant to the Jeanne Clery Disclosure of Campus Security Policy and Campus Crime Statistics Act and the Pennsylvania Act of 1988, Penn State publishes a combined Annual Security and Annual Fire Safety Report (ASR).

    The ASR includes crime statistics and institutional policies concerning campus security, such as those concerning alcohol and drug use, crime prevention, the reporting of crimes, sexual assault, and other matters.

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    Employment with the University will require successful completion of background check(s) in accordance with University policies.

    Penn State is an equal opportunity, affirmative action employe

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